Automated Quantitation of Hemoglobin-Based Blood Substitutes in Whole Blood Samples
نویسندگان
چکیده
منابع مشابه
Hemoglobin-based red blood cell substitutes.
Polyhemoglobin is already well into the final stages of clinical trials in humans with one approved for routine clinical use in South Africa. Conjugated hemoglobin is also in ongoing clinical trials. Meanwhile, recombinant Hb has been modified to modulate the effects of nitric oxide. Other systems contain antioxidant enzymes for those clinical applications that may have potential problems relat...
متن کاملNanobiotechnology for hemoglobin-based blood substitutes.
Nanobiotechnology is the assembling of biological molecules into nanodimension complexes. This has been used for the preparation of polyhemoglobin formed by the assembling of hemoglobin molecules into a soluble nanodimension complex. New generations of this approach include the nanobiotechnological assembly of hemoglobin, catalase, and superoxide dismutase into a soluble nanodimension complex. ...
متن کامل[Hemoglobin-based blood substitutes: current status and perspectives].
BACKGROUND AND OBJECTIVES Alternatives to red blood cells transfusion have been studied since the fifties. This study aimed at presenting current status and perspectives of hemoglobin-based blood substitutes. CONTENTS Potential application areas are presented, in addition to clinical studies involving major hemoglobin molecules developed, their advantages and limitations. CONCLUSIONS Severa...
متن کاملPBLD 5: Current Status of Hemoglobin Free Blood Substitutes
CASE #1: 80 year old female with a history of dypsnea on exertion (DOE) and syncope. Workup reveals aortic stenosis (AVA=0.8cm2) and normal coronary arteries by cardiac catheterization with moderate concentric hypertrophy and an EF of 50%. Her other PMH is unremarkable. She was advised by her cardiac surgeon to seek a preoperative anesthetic consultation because she joined the Watch Tower organ...
متن کاملBlood and blood substitutes.
Each year, in Europe, approximately seven million units of colloidal plasma substitutes are given to patients. Often they are used uncritically, which may account for the increased incidence of sideeffects which has been noted over the last decade. Their increasing use is understandable in view of the disadvantages of using blood; these include the difficulties in finding sufficient donors of a...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2001
ISSN: 0002-9173,1943-7722
DOI: 10.1309/38lc-5k57-mbfx-vx6d